Table 4 Polymorphisms and alternative splicing in ATR gene
From: Alterations of DNA damage-response genes ATM and ATR in pyothorax-associated lymphoma
Cell lines | Nucleotide sites | Alternative splicing Del exon 6 | |||||
|---|---|---|---|---|---|---|---|
379, 380 a | 737 | 1881 | 1920 | 5313 | 7980 a | ||
CGC → GCC | ATG → ACG | GGT → GGA | GAT → GAC | TAT → TAC | CAA → CAG | ||
(Arg → Ala) b | (Met → Thr) b | (Gly → Gly) b | (Asp → Asp) b | (Tyr → Tyr) b | (Gln → Gln) b | ||
OPL-1 | GC | C | A | C | C | A | − |
OPL-2 | GC | C/T | A | C | C/T | G | − |
OPL-3 | GC | T | T | T | T | G/A | − |
OPL-4 | GC | C/T | A/T | C | T | A | − |
OPL-5 | GC | C/T | A/T | T | T | G/A | − |
OPL-7 | GC | T | T | T | T | A | − |
Pal-1 | CG | C/T | A | C/T | C/T | A | + |
Deglis | CG | C | A | T | C/T | A | + |
