Figure 2 | Laboratory Investigation

Figure 2

From: Prolonged β-catenin stabilization and tcf-dependent transcriptional activation in hyperplastic cutaneous wounds

Figure 2

Semiquantitative RT-PCR results for the expression of FN, MMP-7, α-smooth muscle actin (αSMA), type three collagen (COL3A1), and β-catenin. Panel a shows a representative PCR result from a normally healing wound 4 weeks following the initial insult. There is a significant increase in FN, MMP-7, α-smooth muscle actin, and type three collagen expression 4 weeks following the insult, but no change in β-catenin mRNA level compared to that of the control, normal tissue. GAPDH expression is used as a control. Panel b shows relative expression of the various genes at different time points following the initial insult in normal wound healing as in hyperplastic wounds, compared to the control gene, GAPDH. The value for normal skin is given in the last bar in the graph. Error bars are 95% confidence intervals.

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