Figure 4 | Laboratory Investigation

Figure 4

From: MHC-independent genetic regulation of liver damage in a mouse model of autoimmune hepatocellular injury

Figure 4

BALB-background necroinflammatory liver disease in TGF-β1−/− mice is recessively inherited. Litters from TGF-β1+/− intercrosses on the genetic backgrounds shown were killed at postnatal day 11–12 and plasma samples were collected for AST and ALT analyses. Bars show means+SD for TGF-β1 wild-type (+/+) heterozygous (+/−) and knockout (−/−) mice, respectively, within each genetic background. The numbers (n) of mice analyzed in each group are shown below the bars. Corresponding statistical analyses are shown in Table 3. F1: Intercross between 129/CF-1-TGF-β1+/− mice and BALB/c-TGF-β1+/− mice.

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