Table 2 Statistical analyses of plasma AST and ALT levels for H-2 congenic TGF-β1−/− mice and littermate control mice

From: MHC-independent genetic regulation of liver damage in a mouse model of autoimmune hepatocellular injury

Strain, TGF-β1 genotype

Analyte

vs Strain, TGF-β1 genotype

  

Littermatea +/+

Littermatea +/−

BALB/c −/−

BALB.B −/−

BALB.K −/−

129/CF-1 −/−

BALB/c −/−

AST

<0.0001b

<0.0001

N/A

NS

NS

<0.0001

BALB.B −/−

AST

0.0002

<0.0001

NS

N/A

NS

<0.0001

BALB.K −/−

AST

<0.0001

<0.0001

NS

NS

N/A

<0.0001

129/CF-1 −/−

AST

NS

0.03

<0.0001

<0.0001

<0.0001

N/A

BALB/c −/−

ALT

<0.0001

<0.0001

N/A

NS

NS

<0.0001

BALB.B −/−

ALT

0.0003

0.0008

NS

N/A

NS

<0.0001

BALB.K −/−

ALT

0.006

<0.0001

NS

NS

N/A

<0.0001

129/CF-1 −/−

ALT

NS

0.04

<0.0001

<0.0001

<0.0001

N/A

  1. aComparison is between TGF-β1 knockout mice and either wild-type or heterozygous mice from within the same genetic background.
  2. bThe numbers indicate the P-value calculated in group–group comparison using the Student's t-test.
  3. NS: P-value not significant (>0.05); N/A: not applicable.
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