Figure 1
From: A noninvasive genetic screening test to detect oral preneoplastic lesions
Unprocessed MLPA data of DNA derived from normal oral mucosa (upper panels) and from a dysplastic surgical margin (lower panels), all paraffin-embedded tissue. Duplicate MLPA analyses are indicated as exp. 1 and exp. 2. On the x-axis, the number of base pairs is depicted, and on the y-axis, the fluorescence intensity. The lower left arrow indicates a gain of 11q and the lower right arrow indicates a loss of 17p in the DNA of the dysplastic sample. Besides these two genetic changes, a considerable number of other alterations can be observed in the dysplastic sample.
