Table 1 Details of MLPA probes and performance in normal DNA

From: A noninvasive genetic screening test to detect oral preneoplastic lesions

Probe name

Length (bases)

Chromosome position

Confidence interval lower limit

Confidence interval upper limit

CTSB-D01

127

08p22

0.7767

1.2876

CREM-D01

133

10p12.1

0.7343

1.3618

ERBB2-D02

139

17q21.1

0.7373

1.3563

DLEU-D01

147

13q14.3

0.732

1.3662

MLH1-D02

152

03p21.3

0.7744

1.2914

BCL2L1-D01

159

20q11.1

0.7712

1.2967

CASPG-D01

166

04q25

0.8441

1.1847

MYBL2-D01

174

20q13.1

0.6393

1.5643

N33-D01

184

08p22

0.7052

1.418

PMAIP1-D01

192

18q21

0.68

1.4705

CDKN2A-D01

201

09p21

0.783

1.2771

CDKN2B-D01

210

09p21

0.4073

2.4554

TANK-D01X

218

02q24

0.7996

1.2506

EMS1-D01

228

11q13

0.6849

1.4602

IGSF4-D02

236

11q23

0.7921

1.2624

STK11-D02

245

19

0.5655

1.7683

IL1A-D01

255

02q14

0.8024

1.2462

CDKN2D-D01

263

19p13

0.7069

1.4147

BCL2-D01

273

18q21.2

0.8073

1.2387

LMNA-D01

282

01q21.2

0.7214

1.3862

CCND1-D02

291

11q13

0.7511

1.3314

TP53-D13

299

17p13.1

0.652

1.5337

IL18-D01

309

11q22.2–q22.3

0.7808

1.2808

CDH2-D01

320

18q11.2

0.8052

1.242

RB1-D17

328

13q14.2

0.7409

1.3497

MLH1-D12

337

03p21.3

0.7657

1.3061

TP53-D01

345

17p13.1

0.5759

1.7364

BRCA2-D01

355

13q12.3

0.7971

1.2545

AI651963-D01

364

10p14

0.7343

1.3618

IL2-D01

371

04q26

0.6707

1.4909

BLM-M04

382

15q26.1

0.7579

1.3195

TP53-D06

390

17p13.1

0.7026

1.4233

IGF1R-D01

399

15q25–q26

0.4817

2.0761

TP53-D05

408

17p13.1

0.7305

1.369

RECQL4-D02

418

08q24.3

0.7289

1.3719

PTPN1-D01

425

20q13.1–q13.2

0.6846

1.4607

DCC-D02

434

18q21.1

0.657

1.5221

PTP4A3-D04

443

08q24.3

0.6632

1.5079

CTNNB1-D01

453

03p22

0.6699

1.4928

RENT2-D01

460

10p14

0.7879

1.2692

NRAS-D02

471

01p13.2

0.5821

1.7179

MFHAS1-D01

478

08p23.1

0.6221

1.6076

  1. The 99.99% confidence interval corresponding to a nonaltered DNA content of all probes is presented. These data were based on the median values of 20 DNA samples of blood from noncancer controls.
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