Table 3 Comparison between two types of egfr amplification, EGFR expression and several biomarkers in breast phyllodes tumors
Type of egfr detection | p16 | p21 | p27 | p53 | Cyclin A | Cyclin D1 | Cyclin E | c-kit | c-myc | Ki-67 | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
− | + | − | + | − | + | − | + | − | + | − | + | − | + | − | + | − | + | − | + | |
Whole gene | ||||||||||||||||||||
− | 13 | 38 | 18 | 28 | 4 | 47 | 46 | 5 | 48 | 3 | 37 | 10 | 43 | 8 | 45 | 5 | 34 | 16 | 41 | 10 |
+ | 2 | 4 | 0 | 5 | 0 | 6 | 3 | 3 | 5 | 1 | 6 | 0 | 3 | 3 | 4 | 2 | 2 | 4 | 3 | 3 |
Intron 1 repeat | ||||||||||||||||||||
− | 4 | 28 | 14 | 16 | 4 | 28 | 32 | 0 | 32 | 0 | 25 | 5 | 27 | 5 | 30 | 2 | 19 | 13 | 27 | 5 |
+ | 11 | 12 | 2 | 17 | 0 | 23 | 15 | 8 | 19 | 4 | 16 | 5 | 17 | 6 | 17 | 5 | 16 | 7 | 15 | 8 |
Expression | ||||||||||||||||||||
− | 10 | 37 | 18 | 24 | 4 | 43 | 44 | 3 | 46 | 1 | 35 | 8 | 41 | 6 | 43 | 3 | 32 | 14 | 39 | 8 |
+ | 6 | 5 | 1 | 9 | 0 | 11 | 6 | 5 | 8 | 3 | 9 | 2 | 6 | 5 | 7 | 4 | 5 | 6 | 6 | 5 |
