Figure 2
From: Adenovirus-mediated p53 tumor suppressor gene therapy of osteosarcoma
Functional domains of p53 protein. The human p53 protein consists of 393 amino acids and has several functional domains (indicated by the shaded regions) including an acidic or transactivation domain, a proline-rich domain, a sequence-specific DNA-binding domain, an oligomerization domain, and a C-terminal regulatory domain. See text for details.
