Table 1 Cancer outlier profile analysis (COPA)a: the 15 top ranked genes from Tomlins et al (Science 2005)
From: Bioinformatics approach leads to the discovery of the TMPRSS2:ETS gene fusion in prostate cancer
Rank | % | Score | Gene | Cancer | Reference | Evidence |
|---|---|---|---|---|---|---|
1 | 90 | 21.9 | CDH1 | Melanoma | Bittner et al7 | |
1 | 95 | 20.1 | RUNX1T1 | Leukemia | Valk et al8 | XX |
1 | 95 | 15.4 | PRO1073 | Renal | Vasselli et al9 | X |
1 | 95 | 14.2 | MYH11 | Sarcoma | Segal et al10 | |
1 | 90 | 13.0 | PBX1 | Leukemia | Ross et al11 | XX |
1 | 95 | 10.0 | ETV1 | Prostate | Lapointe et al12 | ** |
1 | 90 | 7.5 | WHSC1 | Myeloma | Tian et al13 | X |
1 | 75 | 5.4 | ERG | Prostate | Dhanasekaran et al14 | ** |
1 | 75 | 5.2 | FOX03A | Breast | Wang et al15 | |
1 | 75 | 4.4 | ERG | Prostate | Welsh et al16 | ** |
1 | 75 | 4.3 | CCND1 | Myeloma | Zhan et al17 | X |
1 | 75 | 3.7 | PCSK7 | Leukemia | Cheok et al18 | |
1 | 75 | 3.4 | ERG | Prostate | Lapointe et al12 | ** |
1 | 75 | 3.4 | ERG | Prostate | Dhanasekaran et al2 | ** |
1 | 75 | 2.6 | IGH@ | Lung | Wigle et al19 |
