Figure 2 | Laboratory Investigation

Figure 2

From: The role of peroxisomal ABC transporters in the mouse adrenal gland: the loss of Abcd2 (ALDR), Not Abcd1 (ALD), causes oxidative damage

Figure 2

(a) Lamellae and lipid profiles (arrows) in an adrenocortical cell. 13-month-old abcd1 KO mouse. Uranyl acetate-lead citrate. (b) Typical ceroid filling the cytoplasm of a probable cortical cell. 30-month-old WT mouse. Uranyl acetate-lead citrate. (c) Typical ceroid (arrow) within an inner cortical cell that is adjacent to another with cholesterol clefts (arrowheads). Six-month-old abcd1 KO treated with DHEAS for 6 months. Uranyl acetate-lead citrate. (d) Scant ceroid (+/−) within inner cortical cells (arrows). Twenty-eight-month-old abcd1 KO mouse treated with 4-PBA for 2 months. D-PAS × 150.

Back to article page