Table 1 Prevalance and intensity of ceroid

From: The role of peroxisomal ABC transporters in the mouse adrenal gland: the loss of Abcd2 (ALDR), Not Abcd1 (ALD), causes oxidative damage

 

N

Age

Sex

Ceroid

(A)

WT

10

9–30 months

Male

± (see text)

abcd1 KO

18

4–28 months

Male

0

abcd2 KO

3

21–23 months

Male

++

abcd1/2 KO

4

19–20 months

Male

++

(B)

abcd1 KO

4

20–36 months

3 Females,

0

   

1 Male

 

abcd2 KO

4

22 months

Male

++

abcd1/2 KO

4

19–23 months

2 Females,

++ (see text)

   

2 Males

 

(C) (4-PBA)

WT

2

22 months

Female

0

abcd1 KO

5

26–31 months

3 Females

± (see text)

   

2 Males

 

abcd2 KO

2

23, 25 months

1 Female

+

   

1 Male

 

abcd1/2 KO

3

21 months

1 Female

+ (see text)

   

2 Males

0

0

Negative

+

A few small deposits

±

Trace positive

++

Several large deposits