Figure 3 | Laboratory Investigation

Figure 3

From: Accelerated senescence of human peritoneal mesothelial cells exposed to high glucose: the role of TGF-β1

Figure 3

Effect of glucose on the production of fibronectin by senescent HPMC. Cells were grown into senescence in the presence of either NG, HG, or equimolar M. (a) The mean fibronectin release by early- and late-passage HPMC. The data derived from 10 experiments with cells from separate donors. (b) Fibronectin mRNA expression by early- and late-passage HPMC as assessed by RT-PCR; a representative experiment of 2 performed. (c) Densitometric fibronectin/β-actin ratios were expressed as a percentage of the value characterizing early-passage control cells.

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