Figure 1 | Laboratory Investigation

Figure 1

From: Decay-accelerating factor but not CD59 limits experimental immune-complex glomerulonephritis

Figure 1

Complement activation and histopathological features of ICGN. Representative IF micrographs show C3 activation in glomeruli of wild-type (a) and CD59 KO (b) mice with ICGN, that was significantly increased in DAF KO (c) and DKO (d) animals. DAF KO and DKO mice also developed mesangial proliferative GN (f) compared to the normal morphology in wild-type and CD59 KO mouse kidneys (e). Magnification, × 400.

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