Figure 3 | Laboratory Investigation

Figure 3

From: Granulocyte colony-stimulating factor improves left ventricular function of doxorubicin-induced cardiomyopathy

Figure 3

Effects of G-CSF on cardiac histology in mice 2 weeks after DOX injection (Protocol 1a). (a) Photomicrographs of histological (H&E and Sirius red-stained) and immunohistochemical (CD45 and Flk-1) preparations of heart specimens from the indicated groups. Arrows point to immunopositive cells; scale bars, 20 μm. (b) Graphs showing morphometric data. Bars are means±s.e.m.; *P<0.05 vs the untreated sham group (DOX (−) and G-CSF (−)); #P<0.05 vs the untreated DOX group (DOX (+) and G-CSF (−)).

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