Figure 8

ERK1/2 phosphorylation (expressed as ratio to total ERK1/2 protein expression) was significantly decreased in cholangiocytes from BDL+RAMH-treated animals compared to cholangiocytes from BDL rats treated with NaCl. Data are mean±s.e.m. of three experiments. ^*P<0.05 vs corresponding value from BDL rats treated with NaCl.