Table 2 Genomic changes previously reported in ACC

Location	Change	Method	No. of cases	% with change	Reference	Comment
6q	Loss	CGH	27	22	³⁸
6q16.1	LOH	Microsatellite PCR	58	14	¹²
6q23.2	LOH	Microsatellite PCR	58	12	¹²
6q23–q25	LOH	Microsatellite PCR	25	43–57	¹⁴	LOH reported for 4 markers in region
6q23-qter	Loss	CGH	24	25	¹¹
6q24.1–q25.1	LOH	Microsatellite PCR	58	45	¹²
6q25-q27	LOH	Microsatellite PCR	10	60	³⁹	Non-informative cases excluded from total
6q25-qter	LOH	Microsatellite PCR	6	33	⁴⁰
6q27	LOH	Microsatellite PCR	58	15.50	¹²
9p21	LOH	Microsatellite PCR	10	10	²⁵
12q	Loss	CGH	24	33	¹¹
12q13.11–q13.13	LOH	Microsatellite PCR	58	26	¹³
12q14.1	LOH	Microsatellite PCR	58	21	¹³
12q23.1	LOH	Microsatellite PCR	58	11	¹³
12q23.3	LOH	Microsatellite PCR	58	9	¹³
12q24.32–q24.33	LOH	Microsatellite PCR	58	22	¹³
13q21–q22	Loss	CGH	24	25	¹¹
16p	Gain	CGH	27	26	³⁸
17p13.1	LOH	Microsatellite PCR	21	48	⁴¹
17q	Gain	CGH	27	15	³⁸
19q	LOH	Microsatellite PCR	NA	40	¹⁵	Non-informative cases excluded from total
19	Gain	CGH	24	38	¹¹	Gain of entire chromosome
22q13	Gain	CGH	27	33	³⁸
22q13	Gain	FISH	57	30	³⁸

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