Figure 6 | Laboratory Investigation

Figure 6

From: Inhibition of proteasome by bortezomib causes intracellular aggregation of hepatic serpins and increases the latent circulating form of antithrombin

Figure 6

HSR on mice livers as produced by bortezomib treatment. Effects on Hsp27, Hsp70, Hsp90 and ubiquitin as shown by immunohistochemistry under light microscopy (a) ( × 100 magnification) and representative blots after SDS-PAGE (b). Arrows on the immunohistochemistry images indicate intracellular accumuli of all the aforementioned proteins.

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