Figure 6
From: The aspartic protease napsin A suppresses tumor growth independent of its catalytic activity

Tumor growth of HEK293 cells in SCID mice. SCID mice were subcutaneously injected with 2 × 106 cells at the dorsal flank. Each group consisted of five mice. Data are mean±s.e.m. Cells expressing wild-type napsin A and napsinD283N showed reduced growth of tumors compared with control cells. Animals with large tumors were killed in accordance with local ethical committee regulations.