Figure 5
From: Oxygen and the liberation of placental factors responsible for vascular compromise
The effect of oxygen-conditioned explant medium on angiogenesis. (a) Light micrographs showing the appearance of tubules formed by UtMVEC seeded on Matrigel with either 20, 6 or 1% oxygen-conditioned explant medium. Tubule length (b) and tubule number (c) were determined by image analysis. Hypoxic explant medium (1% O2) caused both a significant reduction in average tubule length (b) (P<0.001 Kruskal–Wallis test and Dunn's post hoc analysis) and an increase in the average tubule number (c) (P<0.05 Kruskal–Wallis test and Dunn's post hoc analysis), N=4, n=64. *P<0.05; ***P<0.001.
