Figure 2

Southern blot analyses for identification of somatic MuLV integrations in lymphomas of NFS. V+ mice. DNA samples of spleens (S) and corresponding tail biopsies (T) from NFS.Akv2 mice were digested with EcoRI and hybridized with the ecotropic-specific probe EcoSp. Germline integrations are those also present in tail DNA. One to two somatic integrations are seen in the lymphoma DNAs, whereas the spleen with reactive (R) changes had none.