Figure 3
From: Human Scavenger Receptor B1 Is Involved in Recognition of Apoptotic Thymocytes by Thymic Nurse Cells
Effects of various competitors on binding of apoptotic thymocytes to nursing TEC. A, Fucoidan was added at a final concentration of 100 μg/ml. Nursing TEC were pretreated for 30 minutes with 100 μg/ml anti-CD36 and an isotype-matched control antibody before phagocytosing apoptotic thymocytes. Results are the mean ± se of three experiments. B, Phosphatidylserine (PS) liposomes, but not phosphatidylcholine (PC) liposomes, compete for apoptotic cell binding to nursing TEC. Binding of viable thymocytes was only about 50% that of apoptotic thymocytes and was not affected by PS liposomes. Final total lipid concentration was 0.1 mm. Results are the mean ± se of five experiments. *Significantly different (p < 0.005).
