Table 4 Correlation Between Karyotypic Alterations, FISH, and Immunohistochemical Reactivity in 28 Endometrial Polyps

From: HMGI-C and HMGI(Y) Immunoreactivity Correlates with Cytogenetic Abnormalities in Lipomas, Pulmonary Chondroid Hamartomas, Endometrial Polyps, and Uterine Leiomyomas and is Compatible with Rearrangement of the HMGI-C and HMGI(Y) Genes

Case

Karyotypic alterations

FISH

HMGI–C

HMGI(Y)

 1E

None

Neg

 2E

None

HMGI-C

+

+

 3E

None

Neg

+

 4E

t(6;8)(p10;q10)

HMGI(Y)

+

 5E

t(8;12)(q11;q15)

HMGI-C

+

 6E

None

HMGI-C

 7

−6, add(11)(q21), +r

HMGI(Y)

+

 8E

inv(12)(p13q15)

HMGI-C

+

+

 9E

None

ND

+

10E

t(12;14)(q15;q24-25)

HMGI-C

+

11E

None

Neg

+

12E

t(1;6)(p32;p21)

HMGI(Y)

+

13E

t(6;7)(p21;p15)

HMGI(Y)

+

14E

Non clonal abnormalities, +dmin

HMGI-C

+

15E

t(12;14)(q15;q24)

HMGI-C

+

16E

None

ND

+

+

17E

t(2;6)(q35;p21)

HMGI(Y)

+

18E

t(3;6;12)(q13;q25;q14-15)

HMGI-C

+

19E

None

ND

20E

None

ND

+

21E

t(6;6;10)(q21;p21;q22)

ND

22E

t(6;14)(p21;q24)

HMGI(Y)

+

+

23E

t(6;14)(p21;q24)

HMGI(Y)

+

24E

None

ND

+

25E

t(6;19)(p21q13)

HMGI(Y)

+

26E

t(6;11)(p21;q13)

HMGI(Y)

+

27E

None

ND

+

28E

t(1;6)(p32;p21), t(6;9) (q13-14;q22)

HMGI(Y)

+