Figure 2 | Laboratory Investigation

Figure 2

From: Islet Abnormalities Associated with an Early Influx of Dendritic Cells and Macrophages in NOD and NODscid Mice

Figure 2

Development of peri-insulitis in an NOD female at 10 weeks of age. Staining for CD11c+ dendritic cells (DC), original magnification ×250. Note that CD11c+ DC already infiltrate the islet at stages in which lymphocyte accumulation around the islets is relatively limited (a). Lymphocytes, in contrast, form an infiltrate adjacent to the islet, even if already high numbers of lymphocytes are present (b).

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