Figure 8
From: E-Cadherin and Cadherin-Associated Cytoplasmic Proteins Are Expressed in Murine Mast Cells
Effects of anti-E-cadherin antibody and synthetic decapeptides on mast cell colony formation from BMMC. BMMC maintained in suspension culture were transferred into methylcellulose media, together with mAbs or peptides, and incubated for 10 days. A, Number of mast cell colonies generated in the presence of 20 μg/ml of ECCD-1, ECCD-2, or control rat IgG2b. B, Number of mast cell colonies generated in the presence of 50 μg/ml of E-cadherin peptide 159-68, E-cadherin peptide 232-41, or P-cadherin peptide 175-84. * Significantly different from the corresponding value for isotype-matched control IgG or E-cadherin peptide 159-68 (*p < 0.05).
