Table 3 Enhanced Tumorigenicity of FPCK-1–1 Cells Injected into the Stromal Fibrous Tissues Surrounding Plastic Plate

From: Conversion of Human Colonic Adenoma Cells to Adenocarcinoma Cells Through Inflammation in Nude Mice

5 × 106 cells of adenoma cells injected into nude mice with

Incidence

 

No. of mice with tumor/no. of mice tested

Fibrous stromaa

6/6d

Nontreatedb

0/6d

Sham operatedc

0/6d

  1. aFPCK-1–1 cells (5 × 106 cells/0.1 ml) in PBS suspension were injected into the stromal fibrous tissues surrounding the plastic plate previously implanted sc without FPCK-1–1 cells and removed after 120 days.
  2. bFPCK-1–1 cells (5 × 106 cells/0.1 ml) in PBS suspension were injected into nontreated KSN nude mice.
  3. cFPCK-1–1 cells (5 × 106 cells/0.1 ml) in PBS suspension were injected into sham-operated KSN nude mice.
  4. dp < 0.001 versus adenoma cells injected into nontreated or sham-operated nude mice.
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