Figure 3
From: Immunomorphometric Studies of Proteinuria in Individual Deep and Superficial Nephrons of Rats
A, Comparison of frequency of luminal deposits in TALs within the inner stripe of the outer medulla of ADR rats in sections perpendicular to the axis of medullary rays and longitudinal sections. The linear regression line for these ADR rats is expressed as y = .628x + 19.462, p < .001, r = .948. Regression line probabilities were p < .003 for NX rats, p < .006 for SHRs, and p < .06 for aging SD rats. B, The mean percentages of TALs with luminal rabbit IgG deposits in long-looped (LL) and short-looped (SL) nephrons are shown for SHRs (n = 15) and aging SD (n = 14), ADR (n = 10), and NX rats (n = 10). LL had more deposits than SL nephrons in SHRs and aging SD rats (p < .001), as well as those in ADR rats (p < .02). The LL deposits in SHRs were also significantly larger and more intense than in SL nephrons (≥ 2+ in 56.6 ± 4.4% vs 35.9 ± 4.2%, p < .001). LL nephrons of ADR rats and aging SD rats also had more ≥ 2+ luminal deposits than SL nephrons (p < .013 and p < .028 respectively). However, frequency of LL and SL deposits of NX rats was equivalent (55.5 ± 3.6% vs 58.7 ± 8.6%). (IS, inner stripe of the outer medulla.)
