Figure 2
From: Epigenetic Regulation of Androgen Receptor Gene Expression in Human Prostate Cancers
A, Summarized bisulfite sequencing of androgen receptor (AR) promoter region in prostate cancer (PCa) cell lines. At least 10 clones from each cell line were analyzed to obtain percentage methylation of the 30 CpG dinucleotides. B, Direct PCR sequencing of Region 1 of the AR in DU145 and a normal prostate tissue. In direct bisulfite sequencing data, CpGs were found to be partially methylated, as indicated by C/T, and unmethylated, as indicated by T. C, MSP analysis of AR promoter and exon A. NP, healthy prostate tissue; NB, healthy female breast tissue.
