Figure 8
From: Bcl-2 Family Gene Expression during Severe Hyperoxia Induced Lung Injury
DNA fragmentation in p53-deficient mice. TUNEL staining of p53 (+/+) (A) and p53 (−/−) (B) lungs following 84 hours exposure to hyperoxia. Filled arrow depicts TUNEL-positive debris and cells; open arrow depicts TUNEL-negative cells. Each panel is representative of three animals. Note the abundant TUNEL-positive debris in both p53 wild-type and deficient lungs.
