Figure 5 | Laboratory Investigation

Figure 5

From: Cell Lineage Analysis during Liver Development Using the spfash-Heterozygous Mouse

Figure 5

Two patterns of OTC mosaicism in the periportal region of 15.5-day spfash-heterozygous fetal livers. A, Laminin immunostaining. B, OTC immunostaining in A. Note the OTC-positive patch within a bile duct progenitor (thin arrow). C, Laminin immunostaining. D, OTC immunostaining in C. OTC-positive patches composed of laminin-positive cells and -negative cells are seen (thick arrows). PV, portal vein. Bar indicates 50 μm.

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