Figure 3

A, Relaxant effect of sodium nitroprusside (SN; 15 and 30 nm) in aortic rings (contracted with PE, 100 nm) from sham OVX and OVX rats treated daily with α-zearalenol (ZE; 1 mg/kg, im, in 100 μl of cottonseed oil), ZE plus ICI 182780 (2.5 mg/kg, im, in 100 μl of cottonseed oil), or vehicle (100 μl, im, of cottonseed oil). Each point represents the mean ± sem of six experiments. B, Relaxant effect of SN (15 and 30 nm) in aortic rings (contracted with PE, 100 nm) from sham OVX and OVX rats treated daily with 17β-estradiol (E; 20 μg/kg, im, in 100 μl cottonseed oil), E plus ICI 182780 (2.5 mg/kg, im, in 100 μl of cottonseed oil), and vehicle (100 μl, im, of cottonseed oil). Each point represents the mean ± sem of six experiments.