Figure 1 | Laboratory Investigation

Figure 1

From: Interleukin-11 Up-Regulates Survivin Expression in Endothelial Cells through a Signal Transducer and Activator of Transcription-3 Pathway

Figure 1

Time-dependent induction of survivin mRNA by IL-11 in HUVEC. Confluent HUVEC were made quiescent by culture in media containing 0.1% FCS for 36 hours, after which new media without (control) or with IL-11 (100 ng/ml) was added at the indicated time intervals. Survivin and β-actin RNA were examined by Northern hybridization. In the indicated samples, 5, 6, dichlorobenzimidazole riboside (DRB; 20 μm) was added 30 minutes before the addition of IL-11. Numbers below the survivin panel indicate relative levels based on densitometry. Data are from one of two experiments with similar outcome.

Back to article page