Figure 7 | Laboratory Investigation

Figure 7

From: Interleukin-11 Up-Regulates Survivin Expression in Endothelial Cells through a Signal Transducer and Activator of Transcription-3 Pathway

Figure 7

Survivin mRNA in lungs of CC-10-IL-11 transgene (+) and transgene (−) mice. Total lung mRNA was isolated and analyzed by Northern blotting as described in “Materials and Methods” (upper panel). The amount of 28S and 18S RNA on the Nylon filters was detected by methylene blue staining and was used for comparison of sample loading (lower panel). Numbers below the survivin panel indicate relative levels based on densitometry. Northern blots of two pairs of animals out of four pairs examined, all with similar results, are shown.

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