Figure 4 | Laboratory Investigation

Figure 4

From: Syndecan-4 Deficiency Increases Susceptibility to κ-Carrageenan–Induced Renal Damage

Figure 4

Immunohistochemical staining of syndecan-4 (A to D, and F) and Tamm-Horsfall glycoprotein (E, the section adjacent to B) in the mature kidney, counterstained with hematoxylin (except F). Kidneys from 2-month-old C57BL/6J mice were used, except for F, in which the kidney from a 2-month-old Synd4(−/−) mouse was used. Thin arrows indicate the renal tubules expressing syndecan-4 strongly in the cortex (B), which also express Tamm-Horsfall glycoprotein (E). Arrowheads indicate the glomeruli (C). Thick arrows indicate the capillaries expressing syndecan-4 (D). Pa, papilla; Me, medulla; Co, cortex. Size bars, 100 μm.

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