Table 1 Summary of the “Invasive” and “Noninvasive” HCC Cell Features
Cell type | Matrigel invasion | α3 expression | Ln-5 migration | MMP-2/9 | MT1-MMP | TIMP-2 | |
|---|---|---|---|---|---|---|---|
Invasive cells | Chang | ++ | +++ | ++ | +/− | + | + |
HLE | ++ | +++ | +++ | +/− | + | + | |
HLF | +++ | +++ | +++ | +/− | + | + | |
SK-Hep1 | +++ | +++ | +++ | −/+ | + | + | |
Noninvasive cells | Alexander | − | ± | ± | −/− | + | + |
Hep3B | − | − | − | −/− | + | + | |
HepG2 | − | − | − | −/− | + | + | |
HepG2.2.15 | − | − | − | −/− | + | + |
