Table 1 Frequency of Allelic Losses at Different Regions on Chromosome 5 in Bladder TCC and Voided Urine Samplesa

From: Mapping and Genome Sequence Analysis of Chromosome 5 Regions Involved in Bladder Cancer Progression

  

Frequency of LOH (%)

  

Bladder tumor samples (n = 37)

Voided urine samples (n = 29)

Deleted regions

Markers

Marker

Region

Marker

Region

5q13.3–q22

D5S428

19.4

24.3

13.6

24.1

 

D5S421

2.8

 

12.0

 
 

APC

5.9

 

7.7

 
 

D5S346

19.4

 

7.7

 

5q22–q31.1b

MCC

5.6

27.0

0.0

27.5

 

D5S659

9.1

 

0.0

 
 

D5S2055

11.1

21.6

16

27.5

 

D5S818

16.7

 

17.9

 

5q31.1-q32

IRF1

8.3

8.1

12.0

17.2

 

CSF1R

2.7

 

11.5

 

5q34

D5S1465

12.5

12.5

4.0

4.0

  1. TCC, transitional cell carcinoma; LOH, loss of heterozygosity.
  2. aRaw data used for this analysis can be obtained from our web site (http://www.mdanderson.org/Departments/GenomeMaps/).
  3. bThe distinct region of allelic losses mapping to 5q22-q31.1 defined by the two neighbor markers (D5S2055 and D5S818) is identified by a solid vertical bar followed by a combined % of LOH for these markers.
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