Figure 7 | Laboratory Investigation

Figure 7

From: Overexpression of the Granulocyte Colony-Stimulating Factor Gene Impairs Bone Morphogenetic Protein Responsiveness in Mice

Figure 7

Number of alkaline phosphatase-positive cells along endosteal surface of the BMP-2/atelocollagen pellet. Alkaline phosphatase-positive cells along endosteal surface were counted as osteoblastic cells and expressed as cell number/mm of endosteal surface. This criteria omitted alkaline phosphatase-positive hematopoietic cells in the marrow. An apparent reduction in the number of osteoblastic cells was observed in the pellets of the G-CSF mice (9.1+/−3.2 cells/mm) compared with those of the control mice (17.8+/−4.1) (n + 6, p < 0.01).

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