Figure 5
Effects of anti-IL4Rα antibody and sIL13Rα2-Fc protein on IL4- and IL13-mediated responses in RCC. The RCC cell line ACHN was cultured with or without IL4 (20 ng/ml), IL13 (20 ng/ml), or IL2 (20 ng/ml), and in the absence or the presence of anti-IL4Rα antibody (10 μg/ml), mouse IgG isotype control (10 μg/ml), or sIL13Rα2-Fc protein (1 μg/ml) for 3 days, as described in “Materials and Methods.” Proliferative response was measured by following (3H)-thymidine uptake during the last 12 hours of culture. Results are expressed in counts per minute (cpm) (mean of triplicates ± sd). Data are representative of three independent experiments.
