Figure 7

Proliferative response to IL13 and IL4 stimulation of transfected cells. The ACHN-transfected cells expressing (clones 27 and 28) the IL13Rα2 chain and mock-transfected cells were cultured with or without one of a series of concentrations of IL4 (black squares) or IL13 (open circles) for 3 days, as described in “Materials and Methods.” The proliferative response was measured by following (3H)-thymidine uptake during last 12 hours of culture. Results are expressed in counts per minute (cpm) (mean of triplicates ± sd). Data are representative of three independent experiments.