Figure 9 | Laboratory Investigation

Figure 9

From: Articular Chondrocytes from Animals with a Dermatan Sulfate Storage Disease Undergo a High Rate of Apoptosis and Release Nitric Oxide and Inflammatory Cytokines: A Possible Mechanism Underlying Degenerative Joint Disease in the Mucopolysaccharidoses

Figure 9

Hydroxyproline content in normal and MPS VI articular cartilage. Articular cartilage from the proximal tibia of 6-month-old healthy and MPS VI rats (n = 3 each) was obtained and hydroxyproline was determined as described in “Materials and Methods” to estimate the total collagen content. Note that there was a significant reduction in the hydroxyproline content of MPS VI compared with normal cartilage (p value <0.05).

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