Table 1 Chromosomal Regions Displaying Significant Gain (>15%) or Loss (>30%) of Genetic Material in a Panel of 36 Familial Ovarian Carcinomas

From: Comparative Genomic Hybridization of Microdissected Familial Ovarian Carcinoma: Two Deleted Regions on Chromosome 15q Not Previously Identified in Sporadic Ovarian Carcinoma

Chromosomal region

No.

Frequency (%)

+8q23-qter

18

50

+3q26.3

18

50

+11q22

11

31

+2q31–32

8

22

+6cent-p23

8

22

+13q22

7

19

+17q24–25

7

19

−8p21-pter

23

64

−16q22-qter

19

53

−22q13

20

53

−9q31–33

16

44

−12q24

16

44

−15q11–15

16

44

−17p12–13

14

39

−Xp21–22

14

39

−20q13

13

36

−15q24–25

12

33

−18q21

12

33

−11p15

11

31

−13q14

11

31

  1. Chromosomes 16 and 19 were excluded from the analysis because of known interpretation difficulties (Kallioniemi et al, 1994; Weiss et al, 1999).
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