Figure 3 | Laboratory Investigation

Figure 3

From: Hyperplasia of Alveolar Neuroendocrine Cells in Rat Lung Carcinogenesis by Silica with Selective Expression of Proadrenomedullin-Derived Peptides and Amidating Enzymes

Figure 3

Serial face-reverse consecutive sections of a hyperplastic alveolar NEB (asterisks) of a silica treated rat at 17 months. A, CGRP immunostaining labels the endocrine cells of the hyperplastic NEB. These hyperplastic cells are also positive for PAMP (B) and PAM (C). D, Immunostaining for AM is negative. Magnification, ×500.

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