Figure 2
From: Abnormal Iron Deposition in Renal Cells in the Rat with Chronic Angiotensin II Administration
Electron microscopy of the proximal tubular epithelial cells in the kidneys of angiotensin II-infused rats. A, The brush border identifies the cell as a proximal tubular epithelial cell. Several lysosomes including electron-dense particles can be seen (arrows). C, No such particles are present in either mitochondria or nuclei. B and D, Higher-magnification images of the bracketed region in A and C, respectively. Secondary lysosome with apparent limiting membrane contains electron dense particles (B), which can be identified as iron particles from their characteristic crystal structure (D). Original magnifications are × 4,000 (A), × 50,000 (B and D), and × 6,000 (C).
