Figure 3
From: Tissue Distribution and Induction of Human Multidrug Resistant Protein 3
Immunohistochemical detection of MRP3 in human gallbladder (a and b) and kidney (c to f) using aminoethyl carbazole as the chromogen. MRP3 was stained with M3II-9. In gallbladder MRP3 staining is observed in the epithelial cells (a). Staining with the negative control antibody in gallbladder is shown in b. In kidney, MRP3 staining is observed in the basolateral membranes of the distal convoluted tubules and, possibly, the thick ascending loops of Henle (c). Positive control stainings for kidney are shown in d (rabbit polyclonal antiserum detecting Tamm-Horsfall protein in the early distal convoluted tubules and the thick ascending loops of Henle), e (MRP2, detected with M2III-6 Mab in the proximal tubuli), and f (rabbit polyclonal antiserum detecting aquaporin-2 in the collecting ducts).
