Figure 4
From: Rho GTPase Inactivation Impairs Lens Growth and Integrity
Ocular phenotypes of C3 transgenic mice. The eyes of 6-week-old mice were dilated with 1% tropicamide and 2.5% phenylephrine hydrochloride, and pictures were recorded with a slitlamp biomicroscope. As compared with wild-type control (A), the transgenic animals developed severe lenticular opacity or cataract (B–D), microphthalmia (C), and intraocular hemorrhage (D). Animals from both lines OD04-11 and OD04-21 exhibited these phenotypes, whereas line OD04-16 animals showed no cataract, microphalmia, or ocular hemorrhage (data not shown). Photographs shown here are from line ODO4-21 mice.
