Table 1 Effect of Exogenous Expression of rae28 on Cardiac Anomalies in rae28−/−

From: Overexpression of Polycomb-Group Gene rae28 in Cardiomyocytes Does Not Complement Abnormal Cardiac Morphogenesis in Mice Lacking rae28 But Causes Dilated Cardiomyopathy

Lines

Animals with reversion/examined

RSV-rae28/rae28 −/−

32/32

βMHC-rae28/rae28 −/−

0/12

  1. rae28−/− embryos with each of the transgenes were examined histoanatomically, and the numbers of animals with reversion of cardiac phenotypes are shown. In addition to reversion of the cardiac anomalies, all the other phenotypes, posterior transformation of the skeletons, systemic neural crest defects, and splenic hypoplasia were also reversed in RSV-rae28/rae28−/−.
Back to article page