Table 2 Echocardiographic Indices

From: Overexpression of Polycomb-Group Gene rae28 in Cardiomyocytes Does Not Complement Abnormal Cardiac Morphogenesis in Mice Lacking rae28 But Causes Dilated Cardiomyopathy

rae28

Wild type

βMHC

 

(n = 8)

(n = 5)

Heart rate (beat per min)

319 ± 89

300 ± 53

LV end-diastolic dimension (mm)

4.1 ± 0.5

5.1 ± 0.6*

LV end-systolic dimension (mm)

2.7 ± 0.4

3.7 ± 0.5**

IVS thickness (mm)

0.7 ± 0.1

0.8 ± 0.1

LV posterior wall thickness (mm)

0.7 ± 0.1

0.7 ± 0.1

Ejection fraction (%)

62 ± 10

52 ± 5*

  1. Five- to 6-month-old βMHC-rae28 and wild type mice were subjected to M-mode echocardiography. Wild type versus βMHC-rae28 were compared using the unpaired Student’s t test.
  2. *p < 0.05,
  3. **p < 0.01 vs. wild type. BW, body weight; LV, left ventricular; IVS, interventricular septal.