Figure 1 | Laboratory Investigation

Figure 1

From: Experimental Immune-Mediated Pancreatitis in Neonatally Thymectomized Mice Immunized with Carbonic Anhydrase II and Lactoferrin

Figure 1

Histopathology of the pancreas in the carbonic anhydrase II (CA-II) experiment. Hematoxylin and eosin-stained tissue sections from nonimmunized neonatal thymectomy (nTx) mice show no lymphocyte infiltration (a). In the nTx mice immunized with CA-II (b and c), moderate lymphocyte infiltration and destruction of the small duct were observed. Lymphocyte infiltration with edematous changes was observed in the nude mice that received whole (d) or CD4+ (e) spleen cells from nTx mice immunized with CA-II. No inflammation was observed in any of the mice that received CD8+ cells (f). Original magnification, ×200 (c) and × 100 (a and b; d–f).

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