Figure 4

Histopathologic detection of collagen in livers. Serial sections of the same tissues in Figure 1 were stained with Azan solution. Liver tissues were obtained from WT (left panels) or TNFRp55-KO (right panels) mice before (a and d), 1 week after (b and e), or 4 weeks after (c and f) the initiation of DMN administration. Blue coloration indicates the presence of collagen. Representative results from at least three individual animals in each group are shown here. Original magnification, × 400.