Figure 6 | Laboratory Investigation

Figure 6

From: Pathogenic Roles of Tumor Necrosis Factor Receptor p55–Mediated Signals in Dimethylnitrosamine-Induced Murine Liver Fibrosis

Figure 6

Changes in gene expression of matrix metalloproteinases (MMPs) and tissue inhibitors of MMPs (TIMPs) after DMN treatment. Total RNAs were extracted from either WT or TNFRp55-KO mice before or 1, 2, and 4 weeks after treatment with DMN. RT-PCR was performed on three individual animals in each group, and representative results are shown (A). The ratio of each PCR product to β-actin was determined, and the relative intensity to untreated WT mice was calculated. Results are expressed as means, and error bars indicate sem (B).

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