Figure 10

Changes in glomerular capillaries and glomerular basement membrane (GBM) in the progression (A–C) and recovery (D) groups on Day 30 (A), Day 60 (B), and Day 100 (C, D). In acute allograft glomerulopathy, injured capillaries separate from GBM with widening subendothelial space. Thereafter, in the progression group, mesangial interposition develops by Day 60, and thickening and duplicated GBM develops by Day 100. By contrast, in the recovery group, glomerular capillaries contact GBM on Day 100, resulting in focal and mild duplication of the GBM. A to D, ×4000.